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Advanced Centre for Treatment Research & Education in Cancer
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Science Sparks @ ACTREC
Date Image 20 January 2020 Vol. No. 9; Issue No. 406
Publications

1. Purandare NC, Puranik A, Shah S, Agrawal A, Gupta T, Moiyadi A, Shetty P, Shridhar E, Patil V, Rangarajan V. Differentiating dural metastases from meningioma: role of ⁶⁸Ga DOTA-NOC PET/CT. Nucl Med Commun. 2020.

2. Gudapati P, Khanka T, Chatterjee G, Ghogale S, Badrinath Y, Deshpande N, Patil J, Narula G, Shetty D, Banavali S, Patkar NV, Gujral S, Subramanian PG, Tembhare PR (2020) - CD304/neuropilin-1 is a very useful and dependable marker for the measurable residual disease assessment of B-cell precursor acute lymphoblastic leukemia. Cytometry B Clinical Cytometry.

3. Chatterjee A, Thota RS, Ramanjulu R, Ahmed A, Bhattacharya D, Salins N, Jain P, Bhatnagar S (2019) - The Indian Society for Study of Pain, Cancer Pain Special Interest Group (SIG) guidelines, for the diagnosis and assessment of cancer pain. Indian Journal of Pain. 33: Suppl S1:1-10.

4. Ramanjulu R, Thota RS, Ahmed A, Jain P, Salins N, Bhatnagar S, Chatterjee A, Bhattacharya D (2019) - The Indian Society for Study of Pain, Cancer Pain Special Interest Group guidelines on pharmacological management of cancer pain (Part I). Indian Journal of Pain. 33: Suppl S1:11-17.

5. Thota RS, Ramanjulu R, Ahmed A, Jain P, Salins N, Bhatnagar S, Chatterjee A, Bhattacharya D (2019). The Indian Society for Study of Pain, Cancer Pain Special Interest Group guidelines on pharmacological management of cancer pain (Part II). Indian Journal of Pain. 33: Suppl S1:18-29.

6. Ramanjulu R, Thota RS, Ahmed A, Jain P, Bhatnagar S, Salins N, Chatterjee A, Bhattacharya D (2019). The Indian Society for Study of Pain, Cancer Pain Special Interest Group guidelines on pharmacological management of cancer pain (Part III). Indian Journal of Pain. 33: Suppl S1:30-36.

7. Ahmed A, Thota RS, Bhatnagar S, Jain P, Ramanjulu R, Salins N, Chatterjee A, Bhattacharya D (2019). The Indian society for study of pain, cancer pain special interest group guidelines on complementary therapies for cancer pain. Indian Journal of Pain. 33: Suppl S1:37-41.

8. Ahmed A, Thota RS, Chatterjee A, Jain P, Ramanjulu R, Bhatnagar S, Salins N, Bhattacharya D (2019) - The Indian Society for Study of Pain, Cancer Pain Special Interest Group guidelines on interventional management for cancer pain. Indian Journal of Pain. 33: Suppl S1: 42-48.

9. Salins N, Thota RS, Bhatnagar S, Ramanjulu R, Ahmed A, Jain P, Chatterjee A, Bhattacharya D (2019) - The Indian Society for Study of Pain, Cancer Pain Special Interest Group guidelines on palliative care aspects in cancer pain management. Indian Journal of Pain 33: Suppl S1: 49-53.

Site of the Week

Genome organizes information on genomes including sequences, maps, chromosomes, assemblies, and annotations.

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Interesting Reads

1. Chan-Seng-Yue M, Kim JC, Wilson GW, Ng K, Figueroa EF, O'Kane GM, Connor AA, Denroche RE, Grant RC, McLeod J, Wilson JM, Jang GH, Zhang A, Liang SB, Borgida A, Chadwick D, Kalimuthu S, Lungu I, Bartlett JMS, Krzyzanowski PM, Sandhu V, Tiriac H, Froeling FEM, Karasinska JM, Topham JT, Renouf DJ, Schaeffer DF, Jones SJM, Marra MA, Laskin J, Chetty R, Stein LD, Zogopoulos G, Haibe-Kains B, Campbell PJ, Tuveson DA, Knox JJ, Fischer SE, Gallinger S, Notta F. Transcription phenotypes of pancreatic cancer are driven by genomic events during tumor evolution. Nat Genet. 2020.

Legends of Science
Rudolf Ludwig Carl Virchow Homi Jehangir Bhabha

Homi Bhabha was an Indian nuclear physicist. He was known as "Father of the Indian nuclear Programme". In January 1933, Bhabha received his doctorate in nuclear physics. In his first scientific paper, "The Absorption of Cosmic radiation", he offered an explanation of the absorption features and electron shower production in cosmic rays. In a paper in the Proceedings of the Royal Society, Series A, he performed the first calculation to determine the cross section of electron-positron scattering. Bhabha gained international prominence after deriving a correct expression for the probability of scattering positrons by electrons, a process now known as “Bhabha Scattering”. Bhabha served as a Reader in the Physics Department of the Indian Institute of Science, Bangalore. With the help of J. R. D. Tata, he played an instrumental role in the establishment of the Tata Institute of Fundamental Research in Mumbai. His major contributions include - work on Compton scattering, R-process, and furthermore the advancement of nuclear physics. He was awarded Padma Bhushan by Government of India in 1954. He later served as a member of the Indian Cabinet's Scientific Advisory Committee and provided the pivotal role to Vikram Sarabhai to set up the Indian National Committee for Space Research, now ISRO. The famed radio telescope in Ooty, India was his initiative, and it became a reality in 1970. He was founding Director of Tata Institute of Fundamental Research (TIFR) and also of the Atomic Energy Establishment, Trombay (AEET) which is now named as the Bhabha Atomic Research Centre (BARC) in his honour. TIFR and AEET/BARC were the cornerstone of Indian development of nuclear weapons which Bhabha supervised as a Director.

Andreas Vesalius Piara Singh Gill

Piara Gill was an Indian nuclear physicist. He was a pioneer in cosmic ray nuclear physics and worked on the American Manhattan project. He was research Professorship fellow of Tata Institute of Fundamental Research (TIFR) (1947), Officer-on-Special Duty (OSD) with the Atomic Energy Commission in New Delhi. He was the first Director of Central Scientific Instruments Organization (CSIO) of India. He established CSIO as a leader in advanced scientific instrument design in Asia. Gill was a key advisor on India's nuclear weapons strategy in the 1950-60s.

Upcoming Events
19th Annual International Conference- RGCON 2020

07-09 February 2020

At JW Marriot Hotel, Aerocity, New Delhi.

International Conference on Hematology

13-14 February 2020

At Novotel London Wembley, 5 Olympic Way HA9 0NP London UK.

The Evolving Landscape of Cancer Modeling

02-05 March 2020

At Hard Rock Hotel, San Diego, California.

Do You Know?

In 1976, Lumpectomy (removal of the tumor only) followed by radiation therapy proved as effective as mastectomy for women with early-stage breast cancer, a finding that dramatically reduced the physical and cosmetic side effects of breast cancer treatment.

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Cancer News
Multimodal genomic analyses predict response to immunotherapy in lung cancer patients

15 January 2020, John Hopkins Medicine

Researchers at Johns Hopkins Kimmel Cancer Center, the Bloomberg Kimmel Institute for Cancer Immunotherapy and the Johns Hopkins University School of Medicine have developed an integrated genomic approach that potentially could help physicians predict which patients with non-small cell lung cancer will respond to therapy with immune checkpoint inhibitors...

Hormone resistance in breast cancer linked to DNA 'rewiring'

16 January 2020, ScienceDaily

Epigenetic changes occur in the DNA of breast cancer cells that have developed a resistance to hormone therapy, an effective treatment for ER+ breast cancer, which accounts for 70% of all diagnoses…

Maintenance therapy with CC-486 extends survival of adults with AML

16 January 2020, National Cancer Institute

An investigational drug extended survival of adults with the blood cancer acute myeloid leukemia (AML), according to results from a large clinical trial. The drug, CC-486, is related to another therapy called azacitidine (Vidaza)…

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